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Appendix O

Appendix O: EPIC-26 Questionnaire

This chapter is general patient education from the book Prostate Cancer, Explained. It is not medical advice for your specific situation. Always discuss your care with your own doctor.

Expanded Prostate Cancer Index Composite — Short Form (EPIC-26)

Patient Name: ____________________________ *Date:* ____________

Date of Birth: ____________ *Medical Record #:* ____________

Instructions: This questionnaire asks about your urinary, bowel, sexual, and hormonal function over the past 4 weeks. Please answer every question by circling the number that best describes your experience. There are no right or wrong answers.

SECTION 1: URINARY INCONTINENCE (Questions 1–4)

1. Over the past 4 weeks, how often have you leaked urine?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

2. Which of the following best describes your urinary control during the past 4 weeks?

No Urinary Control Whatsoever Frequent Dribbling Occasional Dribbling Total Control
1 2 3 4

3. How many pads or adult diapers per day did you usually use to control leakage during the past 4 weeks?

3 or More Pads per Day 1–2 Pads per Day None
1 2 3

4. How big a problem, if any, has dripping or leaking urine been for you during the past 4 weeks?

No Problem Very Small Problem Small Problem Moderate Problem Big Problem
0 1 2 3 4

SECTION 2: URINARY IRRITATIVE/OBSTRUCTIVE (Questions 5–8)

5. Over the past 4 weeks, how often have you had pain or burning with urination?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

6. Over the past 4 weeks, how often have you had blood in your urine?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

7. Over the past 4 weeks, how often have you had a weak urine stream or incomplete emptying?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

8. Overall, how big a problem, if any, has your urinary function been for you during the past 4 weeks?

No Problem Very Small Problem Small Problem Moderate Problem Big Problem
0 1 2 3 4

SECTION 3: BOWEL FUNCTION (Questions 9–14)

9. Over the past 4 weeks, how often have you had urgency to have a bowel movement?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

10. How often have you had uncontrolled leakage of stool during the past 4 weeks?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

11. How often have you had bloody stools during the past 4 weeks?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

12. How often have you had crampy pain in your abdomen, pelvis, or rectum during the past 4 weeks?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

13. How often have you had increased frequency of bowel movements during the past 4 weeks?

Always Usually About Half the Time Seldom Never
1 2 3 4 5

14. Overall, how big a problem, if any, have your bowel habits been for you during the past 4 weeks?

No Problem Very Small Problem Small Problem Moderate Problem Big Problem
0 1 2 3 4

SECTION 4: SEXUAL FUNCTION (Questions 15–20)

15. How would you rate your ability to have an erection during the past 4 weeks?

Very Poor to None Poor Fair Good Very Good
1 2 3 4 5

16. How would you describe the usual quality of your erections during the past 4 weeks?

None at All Not Firm Enough for Any Sexual Activity Firm Enough for Masturbation and Foreplay Only Firm Enough for Intercourse
1 2 3 4

17. How often have you had an erection when you wanted one during the past 4 weeks?

Never Less Than Half the Time About Half the Time More Than Half the Time Whenever I Wanted
1 2 3 4 5

18. How would you rate your ability to reach orgasm (climax) during the past 4 weeks?

Very Poor to None Poor Fair Good Very Good
1 2 3 4 5

19. How would you describe the usual quality of your orgasms during the past 4 weeks?

None Very Poor Fair Good Very Good
1 2 3 4 5

20. Overall, how big a problem, if any, has your sexual function or lack of sexual function been for you during the past 4 weeks?

No Problem Very Small Problem Small Problem Moderate Problem Big Problem
0 1 2 3 4

SECTION 5: HORMONAL FUNCTION (Questions 21–26)

21. Over the past 4 weeks, how often have you experienced hot flashes?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

22. Over the past 4 weeks, how often have you experienced breast tenderness or enlargement?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

23. Over the past 4 weeks, how often have you felt depressed?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

24. Over the past 4 weeks, how often have you felt a lack of energy?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

25. Over the past 4 weeks, how often have you experienced a change in body weight?

More Than Once a Day About Once a Day More Than Once a Week About Once a Week Rarely or Never
1 2 3 4 5

26. Overall, how big a problem, if any, have the above hormonal symptoms been for you during the past 4 weeks?

No Problem Very Small Problem Small Problem Moderate Problem Big Problem
0 1 2 3 4

SCORING SUMMARY

Domain Questions Score Range Your Score
Urinary Incontinence 1–4 0–16 _______
Urinary Irritative/Obstructive 5–8 0–19 _______
Bowel Function 9–14 0–24 _______
Sexual Function 15–20 0–28 _______
Hormonal Function 21–26 0–24 _______

Note: Each domain is scored separately and converted to a 0–100 scale, where higher scores indicate better function. Your doctor or care team will calculate the converted scores.

HOW TO INTERPRET EPIC-26 SCORES

After conversion to the 0–100 scale:

What is a meaningful change?

A change of 6–12 points on the 0–100 scale (depending on the domain) is generally considered clinically meaningful.

WHY THIS QUESTIONNAIRE MATTERS

The EPIC-26 is the most widely used quality-of-life tool specifically designed for prostate cancer patients. It captures the side effects that matter most to patients across all treatment types:

The NCCN guidelines recommend measuring baseline function with a validated instrument such as EPIC-26 before starting any prostate cancer treatment.

TRACKING YOUR SCORES OVER TIME

Date Urinary Incontinence Urinary Irritative Bowel Sexual Hormonal Notes
_____ __ Baseline (before treatment)
_____ __
_____ __
_____ __
_____ __

Notes for your doctor: _______________________________________________